SAP S/4 Change and Compliance Assurance Specialist (1-Year Fixed-Term Contract)

Introduction to the role:

Are you passionate about ensuring quality and compliance in complex business transformation projects? AstraZeneca is seeking a SAP S/4 Change and Compliance Assurance Specialist for a one-year, fixed-term contract within our global AXIAL Programme.

Based in Lisbon, you’ll play a central role in ensuring our SAP S/4HANA system remains robust, validated, and compliant post-deployment—supporting critical change management activities during a high-impact transformation.

Accountabilities:

• Oversee and assure compliance in all post-deployment SAP S/4HANA change management activities, embedding quality and documentation standards across the process.
• Work hands-on with Solution Manager, ServiceNow, and Jira to monitor, support, and validate system changes, ensuring alignment to AstraZeneca’s SOPs and external regulatory requirements (GxP, SOx, Data Integrity, etc.).
• Act as a liaison among project, IT, business, and quality teams, facilitating effective communication on upcoming and ongoing system changes, risks, and compliance issues.
• Maintain and organize thorough, audit-ready documentation supporting inspection readiness for all change activities.
• Integrate change management workflows with computerized system validation (CSV) and quality management processes.
• Confirm that all change management strategies and executions comply with company policies and industry standards.
• Monitor remediation actions related to impact and risk from change management activities, ensuring timely and compliant resolution.
• Support stakeholders with guidance and training on compliant use of change management practices and tools.
• Participate in audit and inspection preparations, delivering clear and complete documentation and responses as required.

Essential Skills/Experience:

• Solid experience in change management or quality assurance for SAP S/4HANA or similar regulated ERP systems.
• Proficient in using Solution Manager, ServiceNow, and Jira for managing system changes and documentation.
• Strong understanding of compliance frameworks and standards such as GxP, ALCOA+, Data Integrity, SOx, and Good Documentation Practices.
• Excellent attention to detail with proven ability to maintain audit-ready documentation.
• Analytical mindset with strong skills in risk assessment, problem-solving, and compliance mitigation.
• Effective communicator with strong interpersonal skills to engage cross-functional and multicultural teams.
• Fluent in English, with strong written and verbal communication abilities.

Desirable Skills/Experience:

• Bachelor’s degree in science, engineering, IT, business, or a related field (or equivalent professional experience).
• Knowledge of agile methodologies and working practices in regulated environments.
• Previous involvement in audit preparation and direct participation in regulatory inspections.
• Strong customer focus and a passion for continuous improvement in quality and compliance controls.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions.

That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, we embrace innovation and collaboration to redefine patient care for the future. With a diverse team of visionary leaders and top talent, we foster an environment where everyone is empowered to share ideas openly. Here, you can make your mark while contributing to healthcare advancements that benefit society.

Ready to take the next step in your career? Apply now and be part of our journey!

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.